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    Canaliculi course through the mineralized matrix connecting adjacent lacunae and allowing contact between thecell processes of neighboring osteocytes (Plate 11, page 244).In this manner, a continuous network of canaliculi and lacu-nae-containing cells and their processes is formed throughoutthe entire mass of mineralized tissue. Is it enough for a newstaff nurse to read a policy and procedure without simulation? Allowing individuals withminimal training to operate complex equipment can be hazardous for patients because ofthe possibility of operator error (27)

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    The effector CD4 and CD8 T cells that Tregs inhibit from functioningduring either an autoimmune response or an anti-tumor response not only elaborate a plethoraof cytokines, but also have the capability to kill target cells using the granulocytic system,which involves injecting perforins into their target. It may be a generalization but informed consent in resource-rich settings islikely to be more rigorous and accountable than that in resource-poor settings(Kiguba et al.

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